ISO/AWI 21686-1
Water quality — In vivo fluorescence measurement of the endocrine disrupting effects of natural water and wastewater using transgenic embryos — Part 1: Thyroid test
Reference number
ISO/AWI 21686-1
Edition 1
Working draft
ISO/AWI 21686-1
A working group has prepared a draft.


This document specifies a method for the determination of the thyroid activity of water and waste water by means of a reporter gene assay with genetically modified Xenopus laevis eleutheroembryos. This method is applicable to: - fresh water; - waste water; - aqueous extracts and leachates; - eluates of sediments (fresh water); - pore water; - aqueous solutions of single substances or of chemical mixtures; - drinking water. The organism preparation methods (freeze-drying, extraction, mineralization) and quantification of the chemical substances do not fall within the scope of this document.

General information

  •  : Under development
    : New project registered in TC/SC work programme [20.00]
  •  : 1
  • ISO/TC 147/SC 5
  • RSS updates

Sustainable Development Goals

This standard contributes to the following Sustainable Development Goal

Got a question?

Check out our Help and Support

Check out our FAQs

Customer care
+41 22 749 08 88

Opening hours:
Monday to Friday - 09:00-12:00, 14:00-17:00 (UTC+1)